Masson-Fontana Melanin Staining Solution? Product Description: Melanin is a non-blood-derived endogenous pigment. It is a group of pigments produced by melanocytes from light brown to black. This pigment usually appears in the epidermis, the eyes, the substantia nigra and the hair follicles of the brain. Melanin has a remarkable physical property, that is, it is completely insoluble in most organic solvents - almost certainly because the melanin formed in melanosome can bind tightly to proteins. Another physical property of melanin is the ability to be bleached by strong oxidants, although the process is slow. In pathological conditions, this pigment can also occur in benign sputum cell tumors and malignant melanoma. In the conventional ?HE? dyeing, it is not black but brown or brownish black. Many methods can be used to identify melanin and melanin-producing cells, such as reduction methods such as Masson-Fonana® silver technology and Schmorl® ferric-potassium ferricyanide reduction experiments; enzymatic methods (eg dopa reaction); fluorescence Method; immunohistochemistry. ?????Masson-Fontana? melanin dyeing using melanin has the function of reducing the silver ammonia solution to metallic silver, that is, the principle of argyrophilic reaction to display melanin, and the melanin is black after dyeing. This method belongs to the common melanin special staining method. Other dyeing is ideal. ?
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